Research Associate II - Type 1 Diabetes Research
City of Hope
Duarte, CA
Job posting number: #7315476 (Ref:10031674)
Posted: August 27, 2025
Application Deadline: Open Until Filled
Job Description
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
A Research Associate II position is available in the laboratory of Dr. Melanie Shapiro, PhD, in the AR-DMRI Department of Diabetes Immunology. You will perform a variety of experiments related to the genetics and immunology of type 1 diabetes.
The Shapiro laboratory currently studies germline genetic variants predicting response to immunotherapies for type 1 diabetes as well as somatic variants in the pancreas and immune cells of organ donors with type 1 diabetes.
For more information on the Shapiro Laboratory please visit here: https://mshapirolab.academicwebsite.com/
For more information on the Arthur Riggs Diabetes & Metabolism Research Institute please visit here: https://www.cityofhope.org/research/riggs-institute/diabetes-milestones-and-history
As a successful candidate, you will:
· Isolate and culture immune cells In vitro
· Perform CRISPR/Cas9-mediated gene editing
· Run multicolor flow cytometry and analysis
· Execute ELISA and/or multiplex cytokine quantification assays
· Analyze single nucleotide polymorphism genotyping data
· Perform murine injections, dissection, and processing of pancreas and immune organs for in vivo experiments
· Process and analyze single cell RNA sequencing data
Your qualifications should include:
· Bachelor’s degree. Masters degree preferred
· 2+ years of related research/laboratory experience with a Bachelor’s degree or 1+ year related research/laboratory experience with a Master’s degree.
· Some experience in the experimental and analytical techniques listed above is preferred, but not required
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, please CLICK HERE.
Salary / Pay Rate Information:
Pay Rate: $33.00 - $51.15 / hour
The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.
City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.
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