Principal Investigator: Srinivasan Dasarathy, MD

Lerner Research Institute Department: Inflammation & Immunity

Lab Research Topics:

• Cell signaling
• RNA translation
• Biochemistry
• Gene editing
• Imaging
• For more information about the lab’s research, please visit: https://www.lerner.ccf.org/immuno/dasarathy/ or contact Dr. Dasarathy at dasaras@ccf.org.

Job Responsibilities:

• Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
• Culture of multiple cell lines, primary cell cultures
• Basic molecular methods (real time PCR, immunoblots)
• Confocal microscopy, fluorescent imaging
• mRNA translational regulation

Education:

• PhD or MD/PhD required
• MD with relevant laboratory experience may substitute for PhD

Languages:

• English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

• Previous experience in a research or academic setting. Graduate student experience meets this requirement.
• Scientific writing experience

Additional Preferred Qualities:

• Crispr/Cas9
• Viral delivery systems
• Handling mouse strains (not essential)
• Protein expression, protein-protein interaction studies
• Fraction separation, organelle isolation
• Ability to analyze and perform mass spectrometry data for metabolites preferred but not essential

Physical Requirements:

• Ability to perform work in a stationary position for extended periods
• Ability to operate a computer and other office equipment
• Ability to communicate and exchange accurate information
• Ability to distinguish color
• Manual dexterity to handle specimens and repair equipment
• Ability to lift and transport equipment or specimens weighing up to 20 pounds
• May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

• PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

• Cover letter
• CV
• Contact information for three references
• All application materials should be submitted directly via email to Dr. Dasarathy at dasaras@ccf.org.

Keywords: Postdoc, Research, LRI, Crispr/Cas9, Skeletal muscle, Tissue specific deletion, Inducible vector systems, Reporter analyses, FRET/BRET, Post-translational modifications, Generate tagged constructs, Subcellular organelle studies